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Breast cancer is the second most common type of cancer worldwide and the most common in women (1,2)
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Given the emerging role for ferroptosis in antitumor immunity, we tested lipophilic statins including simvastatin alone and in combination with Ξ±-PD1 in vivo and found that simvastatin and Ξ±-PD1 promoted tumor clearance and extended survival in 20% to 60% of mice alone but in nearly 100% of mice when administered together
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